بررسی حساسیت آنتی بیوتیکی استافیلوکوک آرئوس به روش E-test در بیمارستان خاتم الانبیای تهران در سال های 92-93

Staphylococcus aureus is a fastidious pathogen of global concern. S. aureus can not only cause a wide range of serious infections, but can also colonize healthy individuals. Nosocomial- associated S. aureus infection is a major concern for healthcare facilities. Recent increases in antibiotic resistance and community-acquired infection highlight the need for improved understanding for prevention and treatment of this pathogen. This study aimed to determine the antibiotic susceptibility pattern of Staphylococcus aureus (SA). This cross sectional study was performed during April 2013-April 2015 among 62 samples of community acquired S. aureus minimal inhibitory concentration (MIC) for various antibiotics against organisms was determined by E-test method and statistical analysis was done by SPSS ver 13. Overall, 62 patients (including 25 women and 37 men) were included in the study. Sensitivity percentage of organisms based on break point used in CLSI M7A6 (Clinical & Laboratory Standard Institute) for various antibiotics. Highest sensitivity was noted to Linezolid (100%) and highest re4sistance was noted against Oxacillin ( 96.1 %). Keywords: MRSA, VISA ,VRSA , E-test, Staphylococcus aureus, Antibiotic resistance